Course: Fundamentals of Biochemistry

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Course title Fundamentals of Biochemistry
Course code UZV/PA1BI
Organizational form of instruction Lecture + Seminar
Level of course Bachelor
Year of study 1
Semester Winter
Number of ECTS credits 2
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Šálek Tomáš, MUDr. Ph.D.
  • Pelková Jana, MUDr.
Course content
Lectures: - Characteristics of living systems (substance composition of organisms) - 1 hour - Biomolecules and water (brief overview and their importance) - 1 hour - Organization of biological systems (living systems from a molecular perspective) - 1 hour - Biop General characteristics of biopolymers (importance, general principles, origin and spatial structure) - 1 hour - Min Amino acids (composition, structure and properties in living systems) - 2 hours - Proteins and peptides (importance, structure and properties) - 1 hour. - Biological function of proteins and properties of protein solutions - 1 hour. - Nucleic acids (nucleotides, structure, DNA, RNA) - 1 hour - High-molecular structures and biomembranes (components of organization, transport of substances) - 2 hours - Enzymes (general characteristics and classification, structure and forms of occurrence) - 1 hour - Enzy Enzyme activity and mechanism of action - 1 hour - Acid-base balance (ABR), material collection, types of ABR disorders, dif. Dg. disorders of ABR, ion metabolism. sodium, potassium - 2 hours Seminars: - Symptoms of blood diseases, propedeutics, medical history - 2 hours - Haematological examinations, blood donations, specifics - 2 hours - Anemia, transfusion - 1 hour - White blood cell disorders - 1 hour - Bood platelets, administration of platelets - 1 hour. - Coagulopathy - bleeding disorders, substitution with blood derivatives - 2 hours - Ag Coagulopathy - thrombotic disorders, thrombophilia, anticoagulant and antithrombotic treatment - 2 hours - Life threatening bleeding - 2 hours - Haematological disorders associated with pregnancy, childbirth and the puerperium - 2 hours

Learning activities and teaching methods
Lecturing, Methods for working with texts (Textbook, book)
  • Participation in classes - 30 hours per semester
  • Home preparation for classes - 30 hours per semester
learning outcomes
Knowledge
define the basic concepts of biochemistry and hematology
define the basic concepts of biochemistry and hematology
explain the procedure for taking biological material
explain the procedure for taking biological material
describe the transfusion aids
describe the transfusion aids
justify deviations from physiological values of blood, urine and other donations
justify deviations from physiological values of blood, urine and other donations
orient in the symptoms of ABR disorders
orient in the symptoms of ABR disorders
Skills
define correct procedures for the collection of biological material for biochemical and haematological examination
define correct procedures for the collection of biological material for biochemical and haematological examination
explain the symptoms of ABR disorders
explain the symptoms of ABR disorders
measure and explain the physiological values of blood, urine and other donations
measure and explain the physiological values of blood, urine and other donations
navigate the issue of blood transfusions
navigate the issue of blood transfusions
describe the procedure for transfusion
describe the procedure for transfusion
teaching methods
Knowledge
Methods for working with texts (Textbook, book)
Methods for working with texts (Textbook, book)
Lecturing
Lecturing
assessment methods
Didactic test
Didactic test
Recommended literature
  • ČERMÁKOVÁ, M., ŠTĚPÁNOVÁ. I. Klinická biochemie. I. díl. Brno: Národní centrum ošetřovatelství a nelékařských zdravotnických oborů v Brně, 2010.
  • Dostál, J. et al. Biochemie pro bakaláře. ISBN 80-210-3232-4.
  • FABER, E. Základy hematologické diagnostiky. Praha: Mladá fronta, 2015.
  • INDRÁK, K. Hematologie a transfuzní lékařství. Praha: Triton, 2014.
  • PELKOVÁ, J. Základy tranfuziologie (Studijní opora). Zlín, 2012.
  • Racek J. et al. Klinická biochemie. ISBN 80-246-0678-X.
  • SEAGER, S., L., SLABAUGH, R., L. Chemistry for today: general, organic, and biochemistry.. Hybrid 8th ed. Belmont, 2014.
  • Schneiderka, P. Kapitoly z klinické biochemie. ISBN 80-246-0678-X.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester