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Lecturer(s)
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Humpolíček Petr, prof. Ing. Ph.D.
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Minařík Antonín, doc. Ing. Ph.D.
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Course content
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- Advanced interactions of biomaterials with cells and tissues. - Interaction of biomaterials with the immune system. Extracellular matter and its relation to biomaterials. - Advanced methods of production of biomaterials and products (medical devices) prepared from them. - Advanced methods of surface functionalization of biomaterials. - Biomaterials based on polymers. - Biomaterials based on ceramics and glass ceramics. - Composite biomaterials, metals. - Fibers and non-woven fabrics. - Carrier systems and systems for the controlled release of active substances. - Gels, hydrogels, aerogels. - Nanomaterials and nanostructures. - In vivo and clinical case studies - materials for the regeneration of skin, mucous membranes and teeth. - In vivo and clinical case studies - materials for bone and organ regeneration. - In vivo and clinical case studies - biosensors.
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Learning activities and teaching methods
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- Preparation for examination
- 150 hours per semester
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| learning outcomes |
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| Knowledge |
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| The student will critically evaluate the key material properties that define an organism's response. |
| The student will critically evaluate the key material properties that define an organism's response. |
| The student will explain the importance of material properties on the functional value of biomaterials. |
| The student will explain the importance of material properties on the functional value of biomaterials. |
| The student will be able to design an experimental procedure to verify the biocompatibility of materials. |
| The student will be able to design an experimental procedure to verify the biocompatibility of materials. |
| The student can search scientific and patent sources for information key to the preparation of biomaterials. |
| The student can search scientific and patent sources for information key to the preparation of biomaterials. |
| Skills |
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| Can plan advanced biosafety experiments, |
| Can plan advanced biosafety experiments, |
| Can plan the characterisation of physicochemical properties. |
| Can plan the characterisation of physicochemical properties. |
| Can analyse and evaluate experiments. |
| Can analyse and evaluate experiments. |
| Can select an appropriate procedure for the preparation of biomaterials. |
| Can select an appropriate procedure for the preparation of biomaterials. |
| teaching methods |
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| Knowledge |
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| Monologic (Exposition, lecture, briefing) |
| Monologic (Exposition, lecture, briefing) |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| Skills |
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| Practice exercises |
| Practice exercises |
| Demonstration |
| Demonstration |
| assessment methods |
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| Knowledge |
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| Didactic test |
| Didactic test |
| Oral examination |
| Oral examination |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
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Recommended literature
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LANZA, R.P., LANGER, R.S., VACANTI, J. Principles of Tissue Engineering. 4th Ed.. Amsterdam: Elsevier. xlviii, 1887 s., 2014. ISBN 9780123983589.
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MA, P.X. Biomaterials and Regenerative Medicine. Cambridge: Cambridge University Press. xvi, 703 s., 2014. ISBN 9781107012097.
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MIGONNEY, V. Biomaterials. London: ISTE. xii, 233 s. Bioengineering and Health Science Series., 2014. ISBN 9781848215856.
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RUYS, A.J. Biomimetic Biomaterials: Structure and Applications. Oxford: Woodhead Publishing. xxvi, 308 s. Woodhead Publishing Series in Biomaterials., 2013. ISBN 9780857094162.
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SNUSTAD, D.P., SIMMONS, M.J., RELICHOVÁ, J., MENDEL, J.G. Genetika. Brno: MU. xxi, 871 s., 2009. ISBN 9788021048522.
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VYMĚTALOVÁ, V. Biologie pro biomedicínské inženýrství. 2. přep. vyd.. Praha: ČVUT, 2016. ISBN 9788001058848.
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