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Lecturer(s)
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Vícha Jan, Mgr. Ph.D.
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Valášková Kristýna, Ing.
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Humpolíček Petr, prof. Ing. Ph.D.
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Víchová Zdenka, doc. Ing. Ph.D.
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Course content
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Legislative framework, ethical aspects 3R principles Methods for assessing biological properties (in vitro, in vivo, in silico) ISO 10 993, OECD standards Cell lines In vitro reconstituted tissues Skin corrosion, skin irritation, eye irritation Skin irritation, sensitisation Phototoxicity, mutagenicity, genotoxicity Reproductive and developmental toxicity Wound healing Drug development and testing
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Learning activities and teaching methods
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- Participation in classes
- 42 hours per semester
- Home preparation for classes
- 18 hours per semester
- Preparation for course credit
- 25 hours per semester
- Term paper
- 35 hours per semester
- Preparation for examination
- 30 hours per semester
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| learning outcomes |
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| Knowledge |
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| The student understands the procedures for testing biological properties of materials. |
| The student understands the procedures for testing biological properties of materials. |
| The student can describe the principles of methods used in the study of biological properties of materials. |
| The student can describe the principles of methods used in the study of biological properties of materials. |
| The student understands the nature of alternative methods of testing biological properties. |
| The student understands the nature of alternative methods of testing biological properties. |
| Skills |
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| The student can critically evaluate a plan of experiments to determine the biological properties of materials. |
| The student can critically evaluate a plan of experiments to determine the biological properties of materials. |
| The student can prepare a biocompatibility test design. |
| The student can prepare a biocompatibility test design. |
| The student masters basic techniques of working in the cell biology laboratory |
| The student masters basic techniques of working in the cell biology laboratory |
| The student can perform and evaluate selected biocompatibility tests. |
| The student can perform and evaluate selected biocompatibility tests. |
| teaching methods |
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| Knowledge |
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| Lecturing |
| Lecturing |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| Skills |
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| Simple experiments |
| Simple experiments |
| Individual work of students |
| Individual work of students |
| assessment methods |
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| Knowledge |
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| Composite examination (Written part + oral part) |
| Composite examination (Written part + oral part) |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
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Recommended literature
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ALBERTS B. et al. Molecular Biology of the Cell. Garland Science, New York, 2002.
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ROSYPAL, S. Nový přehled biologie. Praha: Scientia., 2003.
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SAHU, S.C, CASCIANO, D.A. Nanotoxicity: From in vivo and in vitro Models to Health Risks. Oxford: Wiley-Blackwell, 2009. ISBN 978-0-47074-137-5.
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SNUSTAD, D.P., SIMMONS, M.J., RELICHOVÁ, J. et al. Genetika. Brno: Nakladatelství Masarykovy univerzity., 2009.
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VYMĚTALOVÁ, V. Biologie pro biomedicínské inženýrství. 2. přep. vyd.. Praha: ČVUT, 2016. ISBN 9788001058848.
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