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Lecturer(s)
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Humpolíček Petr, prof. Ing. Ph.D.
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Skopalová Kateřina, Ing. Ph.D.
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Víchová Zdenka, doc. Ing. Ph.D.
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Course content
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1. Cell cycle and its control. Cell aging. Cell death. 2. Nucleic acids. Chromosome bases of heredity. 3. Variability at the level of DNA, RNA and proteins. 4. Gene expression. 5. Omic approaches. 6. Gene imprinting, RNA interference, epigenetics. 7. Basic methods of molecular genetic study. 8. Intercellular connections. Interaction between the cell and its environment. 9. Proliferation, determination, differentiation, migration. 10. Introduction to cell culture, requirements of cells in tissue cultures. 11. Cell types, culture techniques, cell phenotype assessment, cell manipulation. 12. Stem cells. 13. Basic methods of cell biology. 14. Cell pathology.
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Learning activities and teaching methods
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Monologic (Exposition, lecture, briefing), Dialogic (Discussion, conversation, brainstorming)
- Preparation for examination
- 120 hours per semester
- Preparation for course credit
- 40 hours per semester
- Preparation for examination
- 40 hours per semester
- Home preparation for classes
- 32 hours per semester
- Participation in classes
- 8 hours per semester
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| learning outcomes |
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| Knowledge |
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| The student will be able to describe cellular structures and functional relationships between them and their significance for cell behaviour. |
| The student will be able to describe cellular structures and functional relationships between them and their significance for cell behaviour. |
| The student can describe the structures of biomacromolecules and their relevance to cellular physiology. |
| The student can describe the structures of biomacromolecules and their relevance to cellular physiology. |
| The student understands the mechanisms associated with gene expression and their relevance to cell behavior. |
| The student understands the mechanisms associated with gene expression and their relevance to cell behavior. |
| Skills |
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| The student can describe the principles of basic methods of cell biology and molecular genetics. |
| The student can describe the principles of basic methods of cell biology and molecular genetics. |
| teaching methods |
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| Knowledge |
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| Monologic (Exposition, lecture, briefing) |
| Monologic (Exposition, lecture, briefing) |
| Methods for working with texts (Textbook, book) |
| Methods for working with texts (Textbook, book) |
| Skills |
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| Activating (Simulation, games, dramatization) |
| Activating (Simulation, games, dramatization) |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| assessment methods |
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| Knowledge |
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| Didactic test |
| Didactic test |
| Oral examination |
| Oral examination |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
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Recommended literature
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Molecular biology of the cell. 5th ed. New York : Garland Science, 2008. ISBN 978-0-8153-4105-5.
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ALBERTS B. et al. Molecular Biology of the Cell, 5th Ed.. Garland Science, 2008. ISBN 978-0-8153-4105-5.
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COLLINS, F.S. Řeč života: DNA a revoluce v personalizované medicíně. Praha: Academia, Galileo, 2012. ISBN 978-80-200-2161-8.
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FRESHNEY, R. I. Culture of animal cells: a manual of basic technique. 2005. ISBN 0471453293.
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KUCIEL, J., URBAN, T. Principy genetiky. Brno: MU Brno, 2016. ISBN 978-80-7509-385-1.
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Nečas, Oldřich. Obecná biologie pro lékařské fakulty. 3., přeprac. vyd. Jinočany : H & H, 2000. ISBN 8086022463.
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Rosypal, S. Nový přehled biologie. Praha : Scientia, 2003. ISBN 80-7183-268-5.
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ROSYPAL, S. Nový přehled biologie. Praha: Scientia, 2003. ISBN 80-7183-268-5.
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ROSYTAL,S. Nový přehled biologie. Praha: Scientia, 2003.
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SNUSTAD, D.P. a kol. Genetika. Brno: MU, 2009. ISBN 978-80-210-4852-2.
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SNUSTAD, D.P., SIMMONS, M.J., RELICHOVÁ, J. Genetika. Brno: MU Brno, 2005. ISBN 978-80-210-4852-2.
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