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Lecturer(s)
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Kašpárková Věra, doc. Ing. CSc.
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Course content
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- Cosmetics - legislation - Medical devices and biomaterials - legislation. - Sampling and sample preparation. - Physico-chemical methods in the analysis of biomaterials and cosmetics. - Fundametals of potentiometry, conductometry and viscometry - Chromatographic methods, principles, background information. - Liquid and gas chromatography, instrumentation. - Optical methods - basic concepts, classification. - Spectroscopic methods, basics, principles, UV-Vis and IR spectroscopy. - Refractometry and polarimetry - Methods for characterization of dispersion systems (nephelometry and turbidimetry). - Testing of biomaterials - surface and volume properties. - Methods to determine the safety of biomaterials and cosmetics (biocompatibility requirements). - Methods to determine the effectiveness of cosmetics.
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Learning activities and teaching methods
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Lecturing, Simple experiments, Practice exercises
- Preparation for examination
- 120 hours per semester
- Preparation for examination
- 120 hours per semester
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| prerequisite |
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| Knowledge |
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| Fundamental knowledge of physical chemistry. |
| Fundamental knowledge of physical chemistry. |
| learning outcomes |
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| To explain the legislative framework applicable to cosmetic products and medical devices |
| To explain the legislative framework applicable to cosmetic products and medical devices |
| To clarify the fundamentals of chromatographic methods, including instrumentation and evaluation of chromatograms |
| To clarify the fundamentals of chromatographic methods, including instrumentation and evaluation of chromatograms |
| To clarify the theoretical background and application of spectroscopic methods with a focus on UV-Vis and infrared spectroscopy |
| To clarify the theoretical background and application of spectroscopic methods with a focus on UV-Vis and infrared spectroscopy |
| To explain the principles of the methods needed to determine the efficacy and safety of cosmetic products |
| To explain the principles of the methods needed to determine the efficacy and safety of cosmetic products |
| To demonstrate knowledge of characterization methods for characterizing bulk and surface characteristics of biomaterials |
| To demonstrate knowledge of characterization methods for characterizing bulk and surface characteristics of biomaterials |
| Skills |
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| To analyze parabens using HPLC and evaluate the results obtained |
| To analyze parabens using HPLC and evaluate the results obtained |
| To determine the concentration of octanol in the sample using gas chromatography |
| To determine the concentration of octanol in the sample using gas chromatography |
| To use UV-Vis spectroscopy to determine the concentration of two substances in a mixture |
| To use UV-Vis spectroscopy to determine the concentration of two substances in a mixture |
| To evaluate the effect of the commercial cream compositions on pH and skin hydration |
| To evaluate the effect of the commercial cream compositions on pH and skin hydration |
| To prepare liposomes stabilized by selected phospholipids |
| To prepare liposomes stabilized by selected phospholipids |
| teaching methods |
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| Knowledge |
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| Lecturing |
| Lecturing |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| Skills |
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| Simple experiments |
| Simple experiments |
| Practice exercises |
| Practice exercises |
| assessment methods |
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| Knowledge |
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| Grade (Using a grade system) |
| Grade (Using a grade system) |
| Analysis of works made by the student (Technical products) |
| Analysis of works made by the student (Technical products) |
| Analysis of the student's performance |
| Analysis of the student's performance |
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Recommended literature
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AGRAWAL, C.M., ONG, J.L., APPLEFORD, M.R., MANI, G. Introduction to Biomaterials. Basic Theory with Engineering Applications.. Cambridge: Cambridge University Press, 2014. ISBN 978-0-521-11690-9.
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BANDYOPADHYAY, A., BOSE, S. Characterization of Biomaterials.. Amsterdam: Elsevier, 2013. ISBN 9780124158009.
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CHURÁČEK, J. a kol. Analytická separace látek. Praha: SNTL, 1990. ISBN 80-03-00569-8.
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KLOUDA, P. Moderní analytické metody. Ostrava, 2003. ISBN 80-86369-07-2.
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