|
Lecturer(s)
|
-
Šerá Jana, Ing. Ph.D.
-
Riemel Jakub, Ing.
|
|
Course content
|
Bioactive compounds - characterization of natural substances with significant biological effects. Sources of bioactive compounds. Sustainability in biotechnological production of bioactive compounds. Biotechnological production of vitamins - characterization, production organisms, technological processes. Biotechnological production of amino acids and biologically active peptides I. Biotechnological production of amino acids and biologically active peptides II. Microbial production of polysaccharides with significant biological effects. Microbial production of omega-3 polyunsaturated fatty acids. Microbial production of enzymes and their applications. Biotechnological production of antibiotics. Biosynthesis add industrial production of steroids. Cytostatics and cancerostatics. Other important bioactive compounds in pharmacy and their production. Ethics and safety in working with biological substances.
|
|
Learning activities and teaching methods
|
Lecturing, Simple experiments, Teamwork
- Home preparation for classes
- 14 hours per semester
- Preparation for course credit
- 25 hours per semester
- Preparation for examination
- 25 hours per semester
- Participation in classes
- 56 hours per semester
|
| prerequisite |
|---|
| Knowledge |
|---|
| Knowledge of general microbiology. |
| Knowledge of general microbiology. |
| Skills |
|---|
| Work in a (micro)biological laboratory. |
| Work in a (micro)biological laboratory. |
| learning outcomes |
|---|
| Knowledge |
|---|
| List and characterize natural substances with significant biological activity. Describe the sources of bioactive compounds. List the most important groups of organisms used in biotechnology. Describe the biotechnological production of different groups of biologically active compounds. Describe the principles of safe and sustainable work with these substances. |
| List and characterize natural substances with significant biological activity. Describe the sources of bioactive compounds. List the most important groups of organisms used in biotechnology. Describe the biotechnological production of different groups of biologically active compounds. Describe the principles of safe and sustainable work with these substances. |
| Skills |
|---|
| Propose a production process for selected biologically active metabolites. Evaluate organisms suitable for the biotechnological production of additives, including those used in the food industry. Evaluate organisms suitable for the biotechnological production of compounds used in pharmacy, medicine, or environmental protection. Apply basic principles of safety and sustainability in laboratory work. |
| Propose a production process for selected biologically active metabolites. Evaluate organisms suitable for the biotechnological production of additives, including those used in the food industry. Evaluate organisms suitable for the biotechnological production of compounds used in pharmacy, medicine, or environmental protection. Apply basic principles of safety and sustainability in laboratory work. |
| teaching methods |
|---|
| Knowledge |
|---|
| Educational trip |
| Educational trip |
| Lecturing |
| Lecturing |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| Skills |
|---|
| Educational trip |
| Educational trip |
| Students working in pairs |
| Students working in pairs |
| assessment methods |
|---|
| Knowledge |
|---|
| Written examination |
| Written examination |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
|
Recommended literature
|
-
BENVENUTO, M.A. Industrial Biotechnology. Berlin. 2019.
-
KÜCK, U., FRANKENBERG-DINKEL. Biotechnology. Berlin. 2015.
|