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Lecturer(s)
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Jančová Petra, Mgr. Ph.D.
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Course content
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1. Environmental toxicology - introduction, definition, basic principles. 2. Toxicant - factors affecting toxicity of substances; relationships between organism and toxic substance. 3. Basic groups of toxicants monitored in the environment. 4. Biosystem - general properties of living systems, hierarchical arrangement, properties of organisms influencing behaviour to toxicants. 5. Toxicokinetics. 6. Biochemical basis of toxicity. 7. Exposure - general principles, the fate of substances in the environment. 8. Effect - general characteristics, higher levels of toxic effects. 9. Methodologies of ecotoxicology - the evaluation of exposure and effect. 10. Bioindication methods. Ecotoxicological bioassays. 11. Determination of toxicity using models (QSAR). 12. Ecological risk assessment. 13. Waste ecotoxicity. 14. Legislative regulations in ecotoxicology in the Czech Republic.
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Learning activities and teaching methods
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Lecturing
- Participation in classes
- 28 hours per semester
- Home preparation for classes
- 14 hours per semester
- Preparation for examination
- 48 hours per semester
- Participation in classes
- 8 hours per semester
- Home preparation for classes
- 34 hours per semester
- Preparation for examination
- 48 hours per semester
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| prerequisite |
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| Knowledge |
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| Knowledge of toxicology and chemistry (inorganic, organic, analytical, biochemistry). |
| Knowledge of toxicology and chemistry (inorganic, organic, analytical, biochemistry). |
| learning outcomes |
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| list and describe the basic theoretical background of ecotoxicology |
| list and describe the basic theoretical background of ecotoxicology |
| describe the biochemical nature of toxic effects |
| describe the biochemical nature of toxic effects |
| define the environmental impact of major inorganic compounds |
| define the environmental impact of major inorganic compounds |
| characterise the major groups of organic toxicants (organometallic compounds; VOCs; PPCPs; POPs - pesticides, PAHs, PCBs, PCDD/Fs, PBFRs) and describe their impact on the environment |
| characterise the major groups of organic toxicants (organometallic compounds; VOCs; PPCPs; POPs - pesticides, PAHs, PCBs, PCDD/Fs, PBFRs) and describe their impact on the environment |
| list and describe options for exposure and effect assessment |
| list and describe options for exposure and effect assessment |
| list and describe toxicity tests (in vitro, in vivo, in silico, in situ) |
| list and describe toxicity tests (in vitro, in vivo, in silico, in situ) |
| Skills |
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| describe the toxic effects of toxicologically relevant compounds at higher levels |
| describe the toxic effects of toxicologically relevant compounds at higher levels |
| design and apply an appropriate test for (eco)toxicity testing |
| design and apply an appropriate test for (eco)toxicity testing |
| teaching methods |
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| Knowledge |
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| Lecturing |
| Lecturing |
| Methods for working with texts (Textbook, book) |
| Methods for working with texts (Textbook, book) |
| Skills |
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| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| assessment methods |
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| Knowledge |
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| Composite examination (Written part + oral part) |
| Composite examination (Written part + oral part) |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
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Recommended literature
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Anděl, Petr. Ekotoxikologie, bioindikace a biomonitoring. Vyd. 1. Liberec : Evernia, 2011. ISBN 978-80-903787-9-7.
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Klaassen, C.D. Casarett & Doull's Toxicology: The Basic Science of Poisons, Seventh Edition. McGraw-Hill Professional. 2008.
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KLUSOŇ, P. Toxikologie. Ústí nad Labem: UJEP, 2014. ISBN 978-80-7414-811-8.
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KOČÍ, V., MOCOVÁ, K. Ekotoxikologie pro chemiky. Praha: VŠCHT, 2009. ISBN 978-80-7080-699-9.
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LINHART, I. Toxikologie. Praha: VŠCHT, 2014. ISBN 978-80-7080-877-1.
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MOON, T.W., MOMMSEN, T.P. Environmental Toxicology, Volume 6. 1st Ed.. Elsevier Science, 2005. ISBN 9780080458731.
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