Course: Biochemistry I

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Course title Biochemistry I
Course code TUIOZP/TE3BC
Organizational form of instruction Lecture
Level of course Bachelor
Year of study not specified
Semester Winter
Number of ECTS credits 4
Language of instruction English
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Koutný Marek, prof. Mgr. Ph.D.
Course content
- Biochemistry, applications of biochemistry, the composition of living systems, interactions between molecules, the basic principles of the energetics of living organisms. - Amino acids, properties of amino acids, peptide bond, protein, protein folding, description of the 3D structure of proteins. - Enzymes, composition, cofactors, the principles of catalytic function, specificity, enzyme activity, basic enzyme kinetics, affecting the catalytic activity, regulation of activity, enzyme nomenclature, sources and use. - Vitamins. - Nucleotides, nucleic acids, structure, coding and structure of genetic information, expression of genetic information. - Lipids, properties, classification, nomenclature, biological membrane transport. - Carbohydrates, polysaccharides, structure, function, optical isomerism, formulas, properties, classification. - Bioenergetics, ATP and other energy-rich compounds, energy fixation. - Glycolysis, anaerobic metabolism, gluconeogenesis. - Lipid catabolism, beta-oxidation of fatty acids, fatty acid synthesis. - Citric acid cycle and functions, relationship to other metabolic processes, principles of regulation of metabolism. - Respiratory chain, ATP synthesis on the membrane, alternative respiration. - Nitrogen metabolism. - Recap metabolic survey, the relationship of individual organs and tissues for the biochemical processes described.

Learning activities and teaching methods
Monologic (Exposition, lecture, briefing)
  • Home preparation for classes - 15 hours per semester
Learning outcomes
The aim of the subject is to provide the knowledge about composition of living orrganisms, chemical nature of living matter and its structure, principes of enzyme catalysis and information transduction. Students also obtain an overview of major metabolical pathways.
The student is well informed in the terminology, chemical foundation of living organisms and essentional processes in a living cell.
Prerequisites
Knowledge of Organic chemistry I.

Assessment methods and criteria
Oral examination, Written examination

Attendance: active participation on seminaries (an overall attendance minimum of 80%). Passing of all required tests (at least 50% success rate - overall mean value of all tests). Examination: knowledge of the curriculum content already dealt with, written and oral exams. The result of a subject examination is expressed on a six-point scale: A "výborně" (i.e. "excellent"), B "velmi dobře" (i.e. "very good"), C "dobře" (i.e. "good"), D "uspokojivě" (i.e. "satisfactory"), E "dostatečně" (i.e. "sufficient"), F "nedostatečně" (i.e. "fail").
Recommended literature
  • LEHNINGER A., NELSON D.L., YOUNG P. Principles of Biochemistry. W.H. Freeman & Company , 2007.
  • ŠÍPAL Z. a kol. Biochemie. SPN. Praha , 1992. ISBN ISBN 80-0421736-2.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester