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Lecturer(s)
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Janovský Petr, Ing. Ph.D.
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Barbuščáková Zuzana, Mgr.
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Závodná Aneta, Ing.
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Dastychová Lenka, RNDr. Ph.D.
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Rouchal Michal, doc. Ing. Ph.D.
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Kimmel Roman, Ing. Ph.D.
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Vícha Robert, doc. Mgr. Ph.D.
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Course content
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- Ethyl acetate. - 1-bromobutane. - 9,10-anthraquinone. - Acetanilide. - Aminolyses of 1-chloro-2,4-dinitrobenzene with aromatic amine. - Acetylsalicylic acid. - Terc-butylchloride. - Soxhlet extraction of plant leaves pigments. - Methyl 3-nitrobenzoate. - Butyl acetate - green apple flavour. - (E)-benzaldoxime. - Triphenylmethanol. - Dibenzylidenacetone. - 2,4,5-triphenylimidazole. - Dimerization of 2,4,5-triphenylimidazole. - Isolation of cloves essence. - Piperine (isolation of pepper alcaloid). - Methylparabene (Fisher esterification). - Cinnamic acid (Knoevenagel synthesis). - Methyl cinnamate - cinnamon flavour. - 2-Acetylphenyl benzoate. - 1-(2-Hydroxyphenyl)-3-phenylpropane-1,3-dione. - Flavone.
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Learning activities and teaching methods
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Simple experiments
- Home preparation for classes
- 53 hours per semester
- Participation in classes
- 12 hours per semester
- Preparation for course credit
- 25 hours per semester
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| learning outcomes |
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| Knowledge |
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| basic computational operations necessary for the realization of organic synthesis |
| basic computational operations necessary for the realization of organic synthesis |
| practical use of basic methods of organic synthesis for the preparation of selected groups of organic compounds |
| practical use of basic methods of organic synthesis for the preparation of selected groups of organic compounds |
| Skills |
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| perform intermediate organic synthesis reactions |
| perform intermediate organic synthesis reactions |
| apply laboratory operations, such as extraction, Soxhlet extraction, distillation, azeotropic distillation, steam distillation, crystallization, filtration, and suction. |
| apply laboratory operations, such as extraction, Soxhlet extraction, distillation, azeotropic distillation, steam distillation, crystallization, filtration, and suction. |
| use basic spectral methods to characterize organic compounds using refraction index and melting point measurements, thin layer chromatography etc. |
| use basic spectral methods to characterize organic compounds using refraction index and melting point measurements, thin layer chromatography etc. |
| teaching methods |
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| Knowledge |
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| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| Methods for working with texts (Textbook, book) |
| Methods for working with texts (Textbook, book) |
| Skills |
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| Simple experiments |
| Simple experiments |
| Practice exercises |
| Practice exercises |
| assessment methods |
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| Knowledge |
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| Grade (Using a grade system) |
| Grade (Using a grade system) |
| Analysis of works made by the student (Technical products) |
| Analysis of works made by the student (Technical products) |
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Recommended literature
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ARMAREGO, W.R.F., CHAI, C. Purification of laboratory chemicals. Butterworth-Heinemann, 2017. ISBN 978- 0128054574.
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LIŠKA, F. Konstituce, konformace, konfigurace v organickém názvosloví. 2. vyd.. Praha: VŠCHT, 2023. ISBN 978-80-7592-147-5.
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McMURRY, J. Organická chemie. 1. vyd.. Praha: VŠCHT, 2015. ISBN 978-80-7080-930-3.
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PAVIA, D.L. A small scale aproach to organic laboratory practise. Cengage Learning, 2015. ISBN 978- 130525392.
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ŠILHÁNOVÁ, A. Laboratoř organické chemie. 1. vyd. Dotisk.. Praha: VŠCHT, 2007. ISBN 978-80-7080-395-0.
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TIETZE, L.F. Reactions and syntheses in the organic chemistry laboratory. John Willey & Sons, 2015. ISBN 978-3527338146.
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Vicha R., Mrkvička V. Laboratorní cvičení z chemie. UTB Zlín, 2007.
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WILLIAMSON, K.L., MASTERS, K.M. Organic experiments: macroscale and microscale. Brooks/Cole ? Cengage Learning, 2011. ISBN 978-0-538-73363-2.
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