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Lecturer(s)
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Kafka Stanislav, doc. Ing. CSc.
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Course content
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- Basic concepts and definitions, principles of interaction of organism and drugs, the development stages of pharmaceuticals. - Analgesics. - Drugs of the central nervous system - general anesthetics, sedatives and hypnotics. - Drugs of the central nervous system - psychopharmaceuticals. - Autonomic nervous system drugs - adrenergic and antiadrenergic drugs. - Autonomic nervous system drugs - cholinergic and anticholinergic drugs. Musculotropic antispasmodic drugs. - Local anesthetics, antitussives and expectorants. - Antialergics and antihistaminics. - Cardiovascular drugs. - Drugs of the gastrointestinal system. - Anti-infective and anti-invasive agents. - Antineoplastics. - Dermatologic drugs. - Methods of drug design, good manufacturing practice.
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Learning activities and teaching methods
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Monologic (Exposition, lecture, briefing), Practice exercises
- Preparation for examination
- 120 hours per semester
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| prerequisite |
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| Knowledge |
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| Knowledge of organic chemistry, methods of synthesis of organic substances. |
| Knowledge of organic chemistry, methods of synthesis of organic substances. |
| learning outcomes |
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| The student is well informed in the general medicinal chemistry. |
| The student is well informed in the general medicinal chemistry. |
| He/she uses basic terms and definitions. |
| He/she uses basic terms and definitions. |
| He/she understands the principles of organism - drug interactions. |
| He/she understands the principles of organism - drug interactions. |
| He/she has knowledge about methods used in drugs design and rules for drugs registration. |
| He/she has knowledge about methods used in drugs design and rules for drugs registration. |
| Skills |
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| The student is able to implement good production practice policy. |
| The student is able to implement good production practice policy. |
| teaching methods |
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| Knowledge |
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| Lecturing |
| Lecturing |
| Methods for working with texts (Textbook, book) |
| Methods for working with texts (Textbook, book) |
| Skills |
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| Practice exercises |
| Practice exercises |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| assessment methods |
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| Knowledge |
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| Didactic test |
| Didactic test |
| Written examination |
| Written examination |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
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Recommended literature
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Hampl, F., Rádl, S., Paleček, J. Farmakochemie. Praha, 2015.
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Hanika, J. Farmaceutické inženýrství. Praha: VŠCHT, 2013.
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Hynie, S. Farmakologie v kostce. 2. vyd.. Praha: Triton, 2009.
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KLEEMANN, A., ENGEL, J., KUTSCHER, B., REICHERT, D. Pharmaceutical Substances, Syntheses, Patents, Applications. 5th Ed.. Stuttgart: Thieme, 2009.
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Komárek, P., Rabišková, M. Technologie léků. 3. vyd.. Praha: Galén, 2006.
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Kuchař, M. a kol. Farmaceutický encyklopedický slovník. Praha, 2014. ISBN 978-80-7080-876-4.
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Lincová, Dagmar. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha : Galén, 2007. ISBN 978-80-7262-373-0.
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LÜLLMANN, H., MOHR, K., WEHLING, M. Farmakologie a toxikologie. Praha: Grada Publishing, 2004.
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