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Lecturer(s)
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Kafka Stanislav, doc. Ing. CSc.
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Course content
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1. Basic concepts and definitions, principles of interaction of organism and drugs, developmental stages of drugs. 2. Analgesics. 3. Central nervous system drugs - general anesthetics, sedatives and hypnotics. 4. Drugs of the central nervous system - psychopharmaceuticals, antiepileptics, anti-parkinson drugs and antimigraine preparations. 5. Drugs of the vegetative nervous system - adrenergics and antiadrenergics. 6. Drugs of the vegetative nervous system - cholinergics and anticholinergics. Myotropic spasmolytics. 7. Local anesthetics, myorelaxants, antitussives and expectorants. 8. Antiallergics and antihistamines. 9. Medicaments of circulatory system. 10. Medicaments of the digestive system. 11. Anti-infectious and anti-invasive substances. 12. Cytostatics. 13. Dermatology. 14. Methods of designing new drugs, good manufacturing practice.
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Learning activities and teaching methods
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- Preparation for examination
- 90 hours per semester
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| prerequisite |
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| Knowledge |
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| Knowledge of organic chemistry, methods of synthesis of organic substances. |
| Knowledge of organic chemistry, methods of synthesis of organic substances. |
| learning outcomes |
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| The student is familiar with general pharmacochemistry. |
| The student is familiar with general pharmacochemistry. |
| He/she masters the basic concepts and definitions. |
| He/she masters the basic concepts and definitions. |
| He/she understands the principles of interaction between the organism and drugs. |
| He/she understands the principles of interaction between the organism and drugs. |
| He/she has knowledge of methods used in drug design and drug registration rules. |
| He/she has knowledge of methods used in drug design and drug registration rules. |
| Skills |
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| The student is able to apply the principles of good manufacturing practice. |
| The student is able to apply the principles of good manufacturing practice. |
| teaching methods |
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| Knowledge |
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| Lecturing |
| Lecturing |
| Methods for working with texts (Textbook, book) |
| Methods for working with texts (Textbook, book) |
| Skills |
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| Practice exercises |
| Practice exercises |
| Dialogic (Discussion, conversation, brainstorming) |
| Dialogic (Discussion, conversation, brainstorming) |
| assessment methods |
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| Knowledge |
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| Didactic test |
| Didactic test |
| Written examination |
| Written examination |
| Grade (Using a grade system) |
| Grade (Using a grade system) |
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Recommended literature
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ANTOŠOVÁ, Z. Farmaceutický encyklopedický slovník. Praha: VŠCHT, 2014. ISBN 978-80-7080-876-4.
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Hampl F., Paleček J. Farmakochemie. Praha, 2002. ISBN 80-7080-495-5.
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Hanika, J. Farmaceutické inženýrství. Praha: VŠCHT, 2013. ISBN 978-80-7080-859-7.
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Hynie, S. Farmakologie v kostce. 2. vyd.. Praha: Triton, 2009.
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KLEEMANN, A., ENGEL, J., KUTSCHER, B., REICHERT, D. Pharmaceutical Substances, Syntheses, Patents, Applications. 5th Ed.. Stuttgart: Thieme, 2009.
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Komárek, P., Rabišková, M. Technologie léků. 3. vyd.. Praha: Galén, 2006.
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Lincová, Dagmar. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha : Galén, 2007. ISBN 978-80-7262-373-0.
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LÜLLMANN; MOHR; WEHLINF. Farmakologie a toxikologie. Praha: Avicenum., 2002.
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PATRICK, G.L. An Introduction to Medicinal Chemistry. 4th Ed.. Oxford University Press, 2009. ISBN 978-0-19-923447-9.
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THOMAS, G. Fundamentals of Medicinal Chemistry.. Wiley, 2003. ISBN 0-470-84307-1.
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