Course: Methods of Organic Materials Synthesis

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Course title Methods of Organic Materials Synthesis
Course code TUCH/TE7MS
Organizational form of instruction Lecture
Level of course Master
Year of study not specified
Semester Winter
Number of ECTS credits 5
Language of instruction English
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
  • Kafka Stanislav, doc. Ing. CSc.
Course content
- Reduction of multiple bonds between hydrogen atoms, hydrogenolysis. - Reduction of functional groups containing oxygen, nitrogen and sulfur atoms. - Oxidation of hydrocarbons. - Oxidation of hydrocarbons derivatives. - Introduction of halogen atoms into molecules addition of hydrogen halides, halogens and hypohalous acids on C=C, displacement of hydrogen atom with a halogen atom. - Introduction of halogen atoms into molecules displacement of hydroxyl group with a halogen atom, conversion of carbonyl compounds into geminal dihalogen derivatives, displacement of a halogen atom with other halogen atom, displacement of a metal atom with a halogen atom. - Nitration, nitrosation and sulfonation. - Alkylation of aliphatic compounds. - Alkylation and acylation of aromatic compounds. - Preparation of organometallic compounds, conversions and synthetic use of especially organomagnesium, organolithium and organozinc compounds. - Diazotisation, displacement of the diazonium group leading to the formation of oxygen, nitrogen and sulfur containing derivatives, azo coupling reactions, carbon-carbon bond formation. - Knoevenagel reaction, phosphorus ylides, Wittig reaction, Horner - Wadsworth - Emmons reaction. - Darzens reaction, sulfur ylides and their exploitation for the preparation of oxirane derivatives. - Protecting groups in organic synthesis. Protection for the hydroxyl, carbonyl, carboxyl and amino groups.

Learning activities and teaching methods
Lecturing, Monologic (Exposition, lecture, briefing)
  • Home preparation for classes - 14 hours per semester
  • Preparation for course credit - 4 hours per semester
  • Preparation for examination - 40 hours per semester
  • Participation in classes - 42 hours per semester
Learning outcomes
The course is aimed to follow up the students' knowledge of organic chemistry, which has been acquired by passing out the subjects Organic chemistry and Organic chemistry II. It is also aimed at broadening and deepening student's knowledge about methods of introduction and transformation of functional groups in molecules of organic compounds.
Student is well informed in problems of introduction and transformation of functional groups in molecules of organic compounds.
Knowledge from courses Organic chemistry II and Organic chemistry.

Assessment methods and criteria
Grade (Using a grade system), Written examination

Attendance: compulsory at seminars. Examination: knowledge of the curriculum content already dealt with, written exam. The result of a subject examination is expressed on a six-point scale: A "výborně" (i.e. "excellent"), B "velmi dobře" (i.e. "very good"), C "dobře" (i.e. "good"), D "uspokojivě" (i.e. "satisfactory"), E "dostatečně" (i.e. "sufficient"), F "nedostatečně" (i.e. "fail").
Recommended literature
  • Červinka O. a kol. Chemie organických sloučenin. SNTL Praha, 1985.
  • McMurry, J. Organická chemie. Brno: VUTIUM, 2007.
  • Svoboda J. a kol. Organická syntéza I. Praha, VŠChT, 2000. ISBN 80-7080-385-1.

Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester