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Lecturer(s)
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Hůrková Věra, MUDr.
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Kovalčík Milan, MUDr.
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Course content
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- Basis of inheritance. Mendels genetics, genetic interaction, different forms of inheritance, epigenetics - 5 hours - Basis of the clinical cytogenetics - 5 hours - Congenital developmental disorders, their classification and etiology - 5 hours - Methods of molecular biology and genetics using in clinical medicine. Mutagenic and teratogenic factors during gravidity - 8 hours - Non-invasive and invasive methods of prenatal diagnostics - 2 hours - Genetic counselling. The ethical issues of clinical genetics - 5 hours
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Learning activities and teaching methods
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Lecturing, Individual work of students
- Participation in classes
- 30 hours per semester
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| learning outcomes |
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| Knowledge |
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| define the basic concepts of genetics, embryology and prenatal diagnosis |
| define the basic concepts of genetics, embryology and prenatal diagnosis |
| explain the procedure for obtaining the client's medical history in the area of genetic testing |
| explain the procedure for obtaining the client's medical history in the area of genetic testing |
| describe the aids and procedure of each invasive and non-invasive examination method |
| describe the aids and procedure of each invasive and non-invasive examination method |
| justify an empathetic approach to clients |
| justify an empathetic approach to clients |
| be familiar with the principles of genetic counseling |
| be familiar with the principles of genetic counseling |
| Skills |
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| communicate with the client when obtaining an anamnesis in the field of genetic testing |
| communicate with the client when obtaining an anamnesis in the field of genetic testing |
| prepare aids for individual invasive and non-invasive examinations |
| prepare aids for individual invasive and non-invasive examinations |
| use an empathetic approach to clients during prenatal examination |
| use an empathetic approach to clients during prenatal examination |
| orientate in the results of genetic counseling |
| orientate in the results of genetic counseling |
| orientate in the results of the examination within the prenatal screening |
| orientate in the results of the examination within the prenatal screening |
| teaching methods |
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| Knowledge |
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| Individual work of students |
| Individual work of students |
| Lecturing |
| Lecturing |
| assessment methods |
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| Didactic test |
| Didactic test |
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Recommended literature
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BROWN, T.A. Gene Cloning and DNA Analysis: An Introduction. 7th Ed.. Chichester: Wiley Blackwell, 2016. ISBN 978-1-119-07256-0.
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FISCHLOVÁ, H. Základy genetiky. . Plzeň: Západočeská univerzita v Plzni, 2011. ISBN 978-80-7043-973-9.
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HÁJEK, Z., KULOVANÝ, E., MACEK, M. Základy prenatální diagnostiky. Praha: Grada , 2000. ISBN 80-7169-391-X.
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KUCIEL, J., URBAN, T. Principy genetiky. Brno: Mendelova univerzita v Brně, 2016.
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NUSSBAUM, R. Klinická genetika. Praha: Triton, 2010. ISBN 978-80-7254-475-2.
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OTOVÁ, B., MIHALOVÁ, R. Základy biologie a genetiky člověka. V Praze: Karolinum, 2012. ISBN 978-80-246-2109-8.
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